PERTinent Updates

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Issue 38

This edition’s featured article highlights the ongoing work of the PERT Interhospital Transfer Project. The recent edition of PERTinent updates brought to you by The PERT Consortium® Education Committee.

Featured article from the PERT Consortium® 

Interhospital Transfer of Patients with Acute Pulmonary Embolism (PE): Challenges and Opportunities.
Rali P, Sacher D, Rivera-Lebron B, Rosovsky R, Elwing JM, Berkowitz J, Mina B, Dalal B, Davis GA, Dudzinski DM, Duval A, Ichinose E, Kabrhel C, Kapoor A, Lio KU, Lookstein R, McDaniel M, Melamed R, Naydenov S, Sokolow S, Rosenfield K, Tapson V, Bossone E, Keeling B, Channick R, Ross CB.Chest. 2021 Jul 14:S0012-3692(21)01336-2.
doi: 10.1016/j.chest.2021.07.013. Online ahead of print.PMID: 34273391



Second consensus document on diagnosis and management of acute deep vein thrombosis: updated document elaborated by the ESC Working Group on aorta and peripheral vascular diseases and the ESC Working Group on pulmonary circulation and right ventricular function.
Mazzolai L, Ageno W, Alatri A, Bauersachs R, Becattini C, Brodmann M, Emmerich J, Konstantinides S, Meyer G, Middeldorp S, Monreal M, Righini M, Aboyans V.Eur J Prev Cardiol. 2021 Jul 13:zwab088.
doi: 10.1093/eurjpc/zwab088. Online ahead of print.PMID: 34254133


Comparison of Surgical Embolectomy and Veno-arterial Extracorporeal Membrane Oxygenation for Massive Pulmonary Embolism. 
Goldberg JB, Spevack DM, Ahsan S, Rochlani Y, Ohira S, Spencer P, Kai M, Malekan R, Spielvogel D, Lansman S.
Semin Thorac Cardiovasc Surg. 2021 Jun 19:S1043-0679(21)00292-6.
doi: 10.1053/j.semtcvs.2021.06.011. Online ahead of print.  PMID: 34157383

Long Term Sequelae 

“Whole life changed” – Experiences of how symptoms derived from acute pulmonary embolism affects life. A qualitative interview study.
Mannerkorpi K. Thromb Res. 2021 Jul 5;205:56-62.
doi: 10.1016/j.thromres.2021.07.004. Epub ahead of print. PMID: 34247098.


Detection of right ventricular dysfunction in acute pulmonary embolism by computed tomography or echocardiography: A systematic review and meta-analysis. 
Chornenki NLJ, Poorzargar K, Shanjer M, Mbuagbaw L, Delluc A, Crowther M, Siegal DM.
J Thromb Haemost. 2021 Jul 10.
doi: 10.1111/jth.15453. Online ahead of print.  PMID: 34245115

From Our Own

Randomized Trial Comparing Standard Versus Ultrasound-Assisted Thrombolysis for Submassive Pulmonary Embolism: The SUNSET sPE Trial.
Avgerinos ED, Jaber W, Lacomis J, Markel K, McDaniel M, Rivera-Lebron BN, Ross CB, Sechrist J, Toma C, Chaer R; SUNSET sPE Collaborators.JACC Cardiovasc Interv. 2021 Jun 28;14(12):1364-1373.
doi: 10.1016/j.jcin.2021.04.049.PMID: 34167677

An original risk score to predict early major bleeding in acute pulmonary embolism:The Syncope, Anemia, Renal Dysfunction (PE-SARD) bleeding score.
Chopard R, Piazza G, Falvo N, Ecarnot F, Besutti M, Capellier G, Schiele F, Badoz M, Meneveau N.
Chest. 2021 Jul 1:S0012-3692(21)01278-2.
doi: 10.1016/j.chest.2021.06.048. Online ahead of print. PMID: 34217683

Catheter Directed Thrombolysis for Acute Pulmonary Embolism Among Elderly Patients (from a Nationwide Cohort Sample). 
Elkaryoni A, Elgendy IY, Walsh K, Allen S, Newman J, Salem M, Krepostman N, Collins M, DeSirkar S, Bunte MC, Darki A.
Am J Cardiol. 2021 Jul 17:S0002-9149(21)00589-0.
doi: 10.1016/j.amjcard.2021.06.030. Online ahead of print. PMID: 34281672 No abstract available.

Venoarterial Extracorporeal Membrane Oxygenation for Acute Massive Pulmonary Embolism: a Meta-Analysis and Call to Action. 
Kaso ER, Pan JA, Salerno M, Kadl A, Aldridge C, Haskal ZJ, Kennedy JLW, Mazimba S, Mihalek AD, Teman NR, Giri J, Aronow HD, Sharma AM.
J Cardiovasc Transl Res. 2021 Jul 19.
doi: 10.1007/s12265-021-10158-0. Online ahead of print.  PMID: 34282541 Review.

Monotherapy Anticoagulation to Expedite Home Treatment of Patients Diagnosed With Venous Thromboembolism in the Emergency Department: A Pragmatic Effectiveness Trial.
Kline JA, Adler DH, Alanis N, Bledsoe JR, Courtney DM, d’Etienne JP, Diercks DB, Garrett JS, Jones AE, Mackenzie DC, Madsen T, Matuskowitz AJ, Mumma BE, Nordenholz KE, Pagenhardt J, Runyon MS, Stubblefield WB, Willoughby CB.Circ Cardiovasc Qual Outcomes. 2021 Jun 21:CIRCOUTCOMES120007600.
doi: 10.1161/CIRCOUTCOMES.120.007600. Online ahead of print. PMID: 34148351

Use of direct oral anticoagulants in patients with obesity for treatment and prevention of venous thromboembolism: Updated communication from the ISTH SSC Subcommittee on Control of Anticoagulation.
Martin KA, Beyer-Westendorf J, Davidson BL, Huisman MV, Sandset PM, Moll S.J Thromb Haemost. 2021 Jul 14.
doi: 10.1111/jth.15358. Online ahead of print. PMID: 34259389

Pulmonary endarterectomy
Mangukia, C., Rali, P., Desai, P. et al.
Indian Journal of Thorac Cardiovasc Surg. 2021 Jun 29

PERT Consortium News


November 23, 2021

Bloodless Thrombectomy for Pulmonary Embolism Evidence and Future Direction


November 03, 2021

Highlights from the 2021 PE Symposium