Supported by

Issue 42

The recent edition of PERTinent updates brought to you by
The PERT Consortium® Education Committee.

Long-Term Risk for Major Bleeding During Extended Oral Anticoagulant Therapy for First Unprovoked Venous Thromboembolism : A Systematic Review and Meta-analysis.

Khan F, Tritschler T, Kimpton M, Wells PS, Kearon C, Weitz JI, Büller HR, Raskob GE, Ageno W, Couturaud F, Prandoni P, Palareti G, Legnani C, Kyrle PA, Eichinger S, Eischer L, Becattini C, Agnelli G, Vedovati MC, Geersing GJ, Takada T, Cosmi B, Aujesky D, Marconi L, Palla A, Siragusa S, Bradbury CA, Parpia S, Mallick R, Lensing AWA, Gebel M, Grosso MA, Thavorn K, Hutton B, Le Gal G, Fergusson DA, Rodger MA; MAJESTIC Collaborators. 

Ann Intern Med. 2021 Oct;174(10):1420-1429.\
doi: 10.7326/M21-1094. Epub 2021 Sep 14.
PMID: 34516270.

Riociguat treatment in patients with chronic thromboembolic pulmonary hypertension: Final safety data from the EXPERT registry.

Ghofrani HA, Gomez Sanchez MA, Humbert M, Pittrow D, Simonneau G, Gall H, Grünig E, Klose H, Halank M, Langleben D, Snijder RJ, Escribano Subias P, Mielniczuk LM, Lange TJ, Vachiéry JL, Wirtz H, Helmersen DS, Tsangaris I, Barberá JA, Pepke-Zaba J, Boonstra A, Rosenkranz S, Ulrich S, Steringer-Mascherbauer R, Delcroix M, Jansa P, Šimková I, Giannakoulas G, Klotsche J, Williams E, Meier C, Hoeper MM; NEW COLLABORATORS LIST.

Respir Med. 2021 Mar;178:106220.
doi: 10.1016/j.rmed.2020.106220. Epub 2020 Nov 12.
PMID: 33540340.

Diuretic vs. placebo in intermediate-risk acute pulmonary embolism: a randomized clinical trial.

Lim P, Delmas C, Sanchez O, Meneveau N, Rosario R, Bouvaist H, Bernard A, Mansourati J, Couturaud F, Sebbane M, Coste P, Rohel G, Tardy B, Biendel C, Lairez O, Ivanes F, Gallet R, Dubois-Rande JL, Fard D, Chatelier G, Simon T, Paul M, Natella PA, Layese R, Bastuji-Garin S.

Eur Heart J Acute Cardiovasc Care. 2021 Oct 11:zuab082.
doi: 10.1093/ehjacc/zuab082. Online ahead of print.
PMID: 34632490

Inpatient Versus Outpatient Acute Venous Thromboembolism Management: Trends and Postacute Healthcare Utilization From 2011 to 2018.

Lutsey PL, Walker RF, MacLehose RF, Norby FL, Evensen LH, Alonso A, Zakai NA.

J Am Heart Assoc. 2021 Oct 8:e020428.
doi: 10.1161/JAHA.120.020428. Epub ahead of print.
PMID: 34622678.

CASE REPORTS

Extracorporeal membrane oxygenation for patients with pulmonary embolism undergoing thrombolysis.

Kluis A, Eisenga J, Squiers J, Dimaio JM, Gable D, Kedora J, Shutze W, George T.
Ann Thorac Surg. 2021 Oct 1:S0003-4975(21)01683-0.

doi: 10.1016/j.athoracsur.2021.08.065. Online ahead of print.
PMID: 34606747

Racial and Ethnic Disparities in Cancer Associated Thrombosis.

Wiredu C, Haynes N, Guerra C, Ky B.Thromb Haemost. 2021 Oct 20.

doi: 10.1055/a-1674-0259. Online ahead of print.
PMID: 34670288

FROM OUR OWN

Acute Management of High- and Intermediate-Risk Pulmonary Embolism in Children: A Review.

Ross C, Kumar R, Pelland-Marcotte MC, Mehta S, Kleinman ME, Thiagarajan RR, Ghbeis MB, VanderPluym CJ, Friedman KG, Porras D, Fynn-Thompson F, Goldhaber SZ, Brandão LR.

Chest. 2021 Sep 26:S0012-3692(21)04057-5.
doi: 10.1016/j.chest.2021.09.019. Online ahead of print.
PMID: 34587483 Review.

The safety and efficacy of systemic versus catheter-based therapies: application of a prognostic model by a pulmonary embolism response team.

Iskandar JP, Hariri E, Kanaan C, Kassis N, Kamran H, Sese D, Wright C, Marinescu M, Cameron SJ.

J Thromb Thrombolysis. 2021 Sep 29.
doi: 10.1007/s11239-021-02576-3. Epub ahead of print.
PMID: 34586572.

Risk for Recurrent Venous Thromboembolism in Patients With Subsegmental Pulmonary Embolism Managed Without Anticoagulation : A Multicenter Prospective Cohort Study.

Le Gal G, Kovacs MJ, Bertoletti L, Couturaud F, Dennie C, Hirsch AM, Huisman MV, Klok FA, Kraaijpoel N, Mallick R, Pecarskie A, Pena E, Phillips P, Pichon I, Ramsay T, Righini M, Rodger MA, Roy PM, Sanchez O, Schmidt J, Schulman S, Shivakumar S, Trinh-Duc A, Verdet R, Vinsonneau U, Wells P, Wu C, Yeo E, Carrier M; SSPE Investigators*. 

Ann Intern Med. 2021 Nov 23. doi: 10.7326/M21-2981. Epub ahead of print. PMID: 34807722.