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ISSUE 32

Welcome to issue 32 of PERTinent Updates, featuring a select group of articles for your review. We aim to inform and update our members with the most recent major developments in the fields of PE/VTE so that we in the PERT Consortium® can continue to be at the leading edge of improving care for this vulnerable and overlooked group of patients.

 See our recent Position Paper in CHEST on how to diagnose and treat patient with PE during COVID-19.

Position Paper

Diagnosis and Treatment of Pulmonary Embolism During the COVID-19 Pandemic: A Position Paper from the National PERT Consortium.
Rosovsky RP, Grodzin C, Channick R, Davis GA, Giri JS, Horowitz J, Kabrhel C, Lookstein R, Merli G, Morris TA, Rivera-Lebron B, Tapson V, Todoran TM, Weinberg AS, Rosenfield K; PERT Consortium.
Chest. 2020 Aug 27:S0012-3692(20)34287-2. doi: 10.1016/j.chest.2020.08.2064.

PE Epidemiology

Time Trends in Pulmonary Embolism Mortality Rates in the United States, 1999 to 2018.
Martin KA, Molsberry R, Cuttica MJ, Desai KR, Schimmel DR, Khan SS.
J Am Heart Assoc. 2020;e016784. doi:10.1161/JAHA.120.016784

PE Treatment – ECMO

Mid-term outcomes with the use of extracorporeal membrane oxygenation for cardiopulmonary failure secondary to massive pulmonary embolism.
Sertic F, Diagne D, Chavez L, Richards T, Berg A, Acker M, Giri JS, Szeto WY, Khandhar S, Gutsche J, Pugliese S, Fiorilli P, Rame E, Bermudez C.
Eur J Cardiothorac Surg. 2020 Jul 28:ezaa189. doi: 10.1093/ejcts/ezaa189. PMID: 32725134

PE Treatment – Surgical Management

Survival and Right Ventricular Function After Surgical Management of Acute Pulmonary Embolism
Joshua B. Goldberg, Daniel M. Spevack, Syed Ahsan, Yogita Rochlani, Tanya Dutta, Suguru Ohira, Masashi Kai, David Spielvogel, Steven Lansman, Ramin Malekan.  J Am Coll Cardiol. 2020 Aug, 76 (8) 903-911.

PE Treatment – Percutaneous Thrombectomy

Percutaneous thrombectomy in patients with massive and very high-risk submassive acute pulmonary embolism.  
Toma C, Khandhar S, Zalewski AM, D’Auria SJ, Tu TM, Jaber WA.
Catheter Cardiovasc Interv. 2020 Aug 31. doi: 10.1002/ccd.29246. Online ahead of print.
PMID: 32866345

PE – Outpatient Management

British Thoracic Society Quality Standards for outpatient management of pulmonary embolism.
Condliffe R, Albert P, Alikhan R, Gee E, Horner D, Hunter L, Jacobs P, Limbrey R, Newnham M, Preston W, Patel S, Smith LJ, Suntharalingam J.
BMJ Open Respir Res. 2020 Aug;7(1):e000636. doi: 10.1136/bmjresp-2020-000636. PMID: 32816797

PERT Consortium – From Our Own

How I Do It: The PERT Concept: A Step-by-Step Approach to Managing PE
Rivera-Lebron BN, Rali PM, Tapson VF.
Chest. 2020;S0012-3692(20)32092-4. doi:10.1016/j.chest.2020.07.065.

Evaluation of the prothrombin fragment 1.2 in patients with coronavirus disease 2019 (COVID-19).
Al-Samkari H, Song F, Van Cott E, Kuter DJ, Rosovsky R.Am J Hematol. 2020 Aug 11:10.1002/ajh.25962. doi: 10.1002/ajh.25962. Online ahead of print.PMID: 32780525

One-Year Echocardiographic, Functional, and Quality of Life Outcomes After Ultrasound-Facilitated Catheter-Based Fibrinolysis for Pulmonary Embolism.
Piazza G, Sterling KM, Tapson VF, Ouriel K, Sharp ASP, Liu PY, Goldhaber SZ.
Circ Cardiovasc Interv. 2020 Aug;13(8):e009012. doi: 10.1161/CIRCINTERVENTIONS.120.009012. Epub 2020 Aug 6. PMID: 32757658