PERTinent Updates:
Issue 27


Issue 27

Welcome to issue 27 of PERTinent Updates, featuring a select group of articles for your review. We aim to inform and update our members with the most recent major developments in the fields of PERT/VTE so that we in the PERT Consortium® can continue to be at the leading edge of improving care for this vulnerable and overlooked group of patients.



Anticoagulant treatment is associated with decreased mortality in severe coronavirus disease 2019 patients with coagulopathy.
Tang N, Bai H, Chen X, Gong J, Li D, Sun Z. J Thromb Haemost. 2020 Mar 27. doi: 10.1111/jth.14817. [Epub ahead of print]
PMID: 32220112
ISTH interim guidance on recognition and management of coagulopathy in COVID‐19.
Jecko Thachil, Ning Tang, Satoshi Gando, Anna Falanga, Marco Cattaneo, Marcel Levi, Cary Clark, Toshiaki Iba. JTH. First published: 25 March 2020.
National Outcomes of Surgical Embolectomy for Acute Pulmonary Embolism.
Percy ED, Shah R, Hirji S, Tartarini R, Yazdchi F, Harloff M, Kaneko T, Pelletier MP. Ann Thorac Surg. 2020 Mar 18. pii: S0003-4975(20)30394-5. doi: 10.1016/j.athoracsur.2020.02.024.
[Epub ahead of print] PMID: 32199827
Variations in Incidence of Venous Thromboembolism in Low-, Middle- and High-Income Countries.
Siegal DM, Eikelboom JW, Lee SF, Rangarajan S, Bosch J, Zhu J, Yusuf S; Venous Thromboembolism Collaboration. Cardiovasc Res. 2020 Mar 6. pii: cvaa044. doi: 10.1093/cvr/cvaa044.
[Epub ahead of print] PMID: 32142099 [PubMed – as supplied by publisher]
Statin use is associated with reduced risk of recurrence in patients with venous thromboembolism.
Stewart LK, Sarmiento EJ. Am J Med. 2020 Mar 11. pii: S0002-9343(20)30043-7. doi: 10.1016/j.amjmed.2019.12.032.
[Epub ahead of print] PMID: 32171773
Uncertain Value of High-sensitive Troponin T for Selecting Patients With Acute Pulmonary Embolism for Outpatient Treatment by Hestia Criteria.
Hendriks SV, Lankeit M, den Exter PL, Zondag W, Brouwer R, Eijsvogel M, Grootenboers MJ, Faber LM, Heller-Baan R, Hofstee HMA, Iglesias Del Sol A, Mairuhu ATA, Melissant CF, Peltenburg HG, van de Ree MA, Serné EH, Konstantinides S, Klok FA, Huisman MV; Vesta Investigators. Acad Emerg Med. 2020 Mar 12. doi: 10.1111/acem.13943. [Epub ahead of print] No abstract available.
PMID: 32163216
Surveillance or no surveillance ultrasonography for deep vein thrombosis and outcomes of critically ill patients: a pre-planned sub-study of the PREVENT trial.
Arabi YM, Burns KEA, Alsolamy SJ, Alshahrani MS, Al-Hameed FM, Arshad Z, Almaani M, Hawa H, Mandourah Y, Almekhlafi GA, Al Aithan A, Khalid I, Rifai J, Rasool G, Abdukahil SAI, Jose J, Afesh LY, Al-Dawood A; Saudi Critical Care Trials Group. Intensive Care Med. 2020 Feb 24. doi: 10.1007/s00134-019-05899-1.

[Epub ahead of print] PMID: 32095845




Diagnosis of chronic thromboembolic pulmonary hypertension after acute pulmonary embolism.
Klok FA, Couturaud F, Delcroix M, Humbert M. Eur Respir J. 2020 Mar 17. pii: 2000189. doi: 10.1183/13993003.00189-2020. [Epub ahead of print] Review.
PMID: 32184319 [PubMed – as supplied by publisher]



From Our Own

Clinical conundrum: concomitant high-risk pulmonary embolism and acute ischemic stroke.
Lio KU, Jiménez D, Moores L, Rali P. Emerg Radiol. 2020 Mar 24. doi: 10.1007/s10140-020-01772-7. [Epub ahead of print] Review.
PMID: 32211984
When Pigs Fly: A Multidisciplinary Approach to Navigating a Critical Heparin Shortage.
Rosovsky RP, Barra ME, Roberts RJ, Parmar A, Andonian J, Suh L, Algeri S, Biddinger PD. Oncologist. 2020 Mar 10. doi: 10.1634/ theoncologist.2019-0910.
[Epub ahead of print] Review.
PMID: 32154634
Evaluating time to treatment and in-hospital outcomes of pulmonary embolism response teams.
Wiske CP, Shen C, Amoroso N, Brosnahan SB, Goldenberg R, Horowitz J, Jamin C, Sista AK, Smith D, Maldonado TS. J Vasc Surg Venous Lymphat Disord. 2020 Mar 13. pii: S2213-333X(20)30066-4. doi: 10.1016/j.jvsv.2019.12.077.
[Epub ahead of print]
PMID: 32179041
Implementation of regional multidisciplinary pulmonary embolism response team – PERT-POZ initial one-year experience.
Sławek-Szmyt S, Jankiewicz S, Smukowska-Gorynia A, Janus M, Klotzka A, Puślecki M, Jemielity M, Krasiński Z, Żabicki B, Elikowski W, Grygier M, Mularek-Kubzdela T, Lesiak M, Araszkiewicz A. Kardiol Pol. 2020 Mar 12. doi: 10.33963/KP.15230.
[Epub ahead of print]
PMID: 32165606
Effect of metabolic syndrome on mean pulmonary arterial pressures in patients with acute pulmonary embolism treated with catheter-directed thrombolysis.
Stewart LK, Beam DM, Casciani T, Cameron SJ, Kline JA. Int J Cardiol. 2020 Mar 1;302:138-142. doi: 10.1016/j.ijcard.2019.12.043. Epub 2019 Dec 26.
PMID: 31948673
Pulmonary vasodilation in acute pulmonary embolism – a systematic review.
Lyhne MD, Kline JA, Nielsen-Kudsk JE, Andersen A. Pulm Circ. 2020 Mar 4;10(1):2045894019899775. doi: 10.1177/2045894019899775. eCollection 2020 Jan-Mar. Review.
PMID: 32180938