PERTinent Updates:
Issue 26



Welcome to issue 26 of PERTinent Updates, featuring a select group of articles for your review. We aim to inform and update our members with the most recent major developments in the fields of PERT/VTE so that we in the PERT Consortium® can continue to be at the leading edge of improving care for this vulnerable and overlooked group of patients.




Epidemiology and outcomes of clinically unsuspected venous thromboembolism in children: a systematic review.
Sharathkumar AA, Biss T, Kulkarni K, Ahuja S, Regan M, Male C, Revel-Vilk S. J Thromb Haemost. 2020 Jan 27. doi: 10.1111/jth.14739. [Epub ahead of print]
PMID: 31984669
Evaluation of the Incidence of Chronic Thromboembolic Pulmonary Hypertension 1 Year After First Episode of Acute Pulmonary Embolism: A Cohort Study.
Rashidi F, Parvizi R, Bilejani E, Mahmoodian B, Rahimi F, Koohi A.
Lung. 2020 Jan 2. doi: 10.1007/s00408-019-00315-3. [Epub ahead of print]
PMID: 31894412




Pulmonary embolism rule out: positivity and factors affecting the yield of CT angiography.

Aggarwal T, Eskandari A, Priya S, Mullan A, Garg I, Siembida J, Mullan B, Nagpal P.
Postgrad Med J. 2020 Jan 5. pii: postgradmedj-2019-137031. doi: 10.1136/postgradmedj-2019-137031. [Epub ahead of print]
PMID: 31907225



Risk Stratification

Validation of a fast prognostic score for risk stratification of normotensive patients with acute pulmonary embolism.
Hobohm L, Becattini C, Konstantinides SV, Casazza F, Lankeit M.
Clin Res Cardiol. 2020 Feb 6. doi: 10.1007/s00392-019-01593-w. [Epub ahead of print]
PMID: 32025793




Effectiveness and Safety of Direct Oral Anticoagulants versus Warfarin in Obese Patients with Acute Venous Thromboembolism.
Coons JC, Albert L, Bejjani A, Iasella CJ.
Pharmacotherapy. 2020 Jan 22. doi: 10.1002/phar.2369. [Epub ahead of print]
PMID: 31968126



Long Term Sequelae

Long-term Risk of Post-Thrombotic Syndrome after Symptomatic Distal Deep-Vein Thrombosis: The CACTUS-PTS Study.
Galanaud JP, Righini M, Le Collen L, Douillard A, Robert-Ebadi H, Pontal D, Morrison D, Barrellier MT, Diard A, Guénnéguez H, Brisot D, Faïsse P, Accassat S, Martin M, Delluc A, Solymoss S, Kassis J, Carrier M, Quéré I, Kahn SR. J Thromb Haemost. 2020 Jan 3. doi: 10.1111/jth.14728. [Epub ahead of print]
PMID: 31899848




Expert opinion on the creating and operating of the regional Pulmonary Embolism Response Teams (PERT). Polish PERT Initiative.
Araszkiewicz A, Kurzyna M, Kopeć G, Roik M, Darocha S, Pietrasik A, Puślecki M, Biederman A, Przybylski R, Stępniewski J, Furdal M, Mularek-Kubzdela T, Pruszczyk P, Torbicki A.
Cardiol J. 2019;26(6):623-632. doi: 10.5603/CJ.2019.0127.
PMID: 31970735



From Our Own

Over-Testing for Suspected Pulmonary Embolism in American Emergency Departments: The Continuing Epidemic.
Kline JA, Garrett JS, Sarmiento EJ, Strachan CC, Courtney DM.
Circ Cardiovasc Qual Outcomes. 2020 Jan;13(1):e005753. doi: 10.1161/CIRCOUTCOMES.119.005753. Epub 2020 Jan 20.
PMID: 31957477
Ultrasound-Accelerated Thrombolysis and Venoplasty for the Treatment of the Postthrombotic Syndrome: Results of the ACCESS PTS Study.
Garcia MJ, Sterling KM, Kahn SR, Comerota AJ, Jaff MR, Ouriel K, Weinberg I; ACCESS PTS Investigators.
J Am Heart Assoc. 2020 Feb 4;9(3):e013398. doi: 10.1161/JAHA.119.013398. Epub 2020 Jan 25.
PMID: 31983322
Recent trends in use of inferior vena caval filters in US older adults with acute pulmonary embolism.
Bikdeli B, Wang Y, Jimenez D, Ross JS, Gupta A, Desai MM, Parikh SA, Monreal M, Goldhaber SZ, Krumholz HM.
Thromb Res. 2020 Feb;186:78-79. doi: 10.1016/j.thromres.2019.12.020. Epub 2019 Dec 27. No abstract available.
PMID: 31901644
Quantification and Significance of Pulmonary Vascular Volume in Predicting Response to Ultrasound-Facilitated, Catheter-Directed Fibrinolysis in Acute Pulmonary Embolism (SEATTLE-3D).
Rahaghi FN, San José Estépar R, Goldhaber SZ, Minhas JK, Nardelli P, Vegas Sanchez-Ferrero G, De La Bruere I, Hassan SM, Mason S, Ash SY, Come CE, Washko GR, Piazza G.
Circ Cardiovasc Imaging. 2019 Dec;12(12):e009903. doi: 10.1161/CIRCIMAGING.119.009903. Epub 2019 Dec 17. No abstract available.
PMID: 31842589
Long-term mortality after massive, submassive, and low-risk pulmonary embolism.
Gupta R, Ammari Z, Dasa O, Ruzieh M, Burlen JJ, Shunnar KM, Nguyen HT, Xie Y, Brewster P, Chen T, Aronow HD, Cooper CJ.
Vasc Med. 2019 Dec 17:1358863X19886374. doi: 10.1177/1358863X19886374. [Epub ahead of print]
PMID: 31845835
Reducing length of stay with the direct oral anti-coagulants in low and intermediate risk pulmonary embolism: a single center experience.
Filopei J, Bondarsky EE, Ehrlich M, Islam M, Bajpayee G, Pang D, Shujaat A, Rowland J, Steiger DJ.
J Thromb Thrombolysis. 2020 Jan 29. doi: 10.1007/s11239-020-02045-3. [Epub ahead of print]
PMID: 31997255