PERTinent Updates:
Issue 19

Welcome to issue 19 of PERTinent Updates, featuring a select group of articles for your review. We aim to inform and update our members with the most recent major developments in the fields of PERT/VTE so that we in the PERT ConsortiumTM can continue to be at the leading edge of improving care for this vulnerable and overlooked group of patients.

Issue Highlight:
From Our Own

• Cardiovascular Risk Factors Associated With Venous Thromboembolism



Long Term Outcomes

Persistent exercise limitation after successful pulmonary endoarterectomy: frequency and determinants

Corsico AG, D’Armini AM, Conio V, Sciortino A, Pin M, Grazioli V, Di Vincenzo G, Di Domenica R, Celentano A, Vanini B, Grosso A, Gini E, Albicini F, Merli VN, Ronzoni V, Ghio S, Klersy C, Cerveri I.
Respir Res. 2019 Feb 14;20(1):34. doi: 10.1186/s12931-019-1002-5.
PMID: 30764853 [PubMed – in process]




Pearls and Myths in the Evaluation of Patients with Suspected Acute Pulmonary Embolism

Stüssi-Helbling M, Arrigo M, Huber LC.
Am J Med. 2019 Jan 30. pii: S0002-9343(19)30114-7.
doi: 10.1016/j.amjmed.2019.01.011. [Epub ahead of print] Review.
PMID: 30710540


Treatment of Superficial Vein Thrombosis: A Systematic Review and Meta-Analysis

Duffett L, Kearon C, Rodger M, Carrier M.
Thromb Haemost. 2019 Feb 4. doi: 10.1055/s-0039-1677793. [Epub ahead of print]
PMID: 30716777 [PubMed – as supplied by publisher]



Risk Stratification

The value of sPESI for risk stratification in patients with pulmonary embolism

Wells P. J Thromb Thrombolysis. 2019
PMID: 30729377



Therapy Related

Extracorporeal membrane oxygenation in life-threatening massive pulmonary embolism.

Kjaergaard B, Kristensen JH, Sindby JE, de Neergaard S, Rasmussen BS.
Perfusion. 2019 Feb 17:267659119830014. doi: 10.1177/0267659119830014.
[Epub ahead of print]
PMID: 30773127


Extracorporeal membrane oxygenation and surgical embolectomy for high-risk pulmonary embolism.

Ius F, Hoeper MM, Fegbeutel C, Kühn C, Olsson K, Koigeldiyev N, Tudorache I, Warnecke G, Optenhöfel J, Puntigam JO, Schäfer A, Meyer BC, Hinrichs JB, Bauersachs J, Haverich A, Cebotari S.
Eur Respir J. 2019 Feb 6. pii: 1801773.
doi: 10.1183/13993003.01773-2018. [Epub ahead of print]
PMID: 30728206



Upcoming Trial

The rationale, design, and methods of a randomized, controlled trial to evaluate the efficacy and safety of an active strategy for the diagnosis and treatment of acute pulmonary embolism during exacerbations of chronic obstructive pulmonary disease.

Jiménez D, Agustí A, Monreal M, Otero R, Huisman MV, Lobo JL, Quezada A, Jara-Palomares L, Hernando A, Tabernero E, Marcos P, Ruiz-Artacho P, Ballaz A, Bertoletti L, Couturaud F, Yusen R; SLICE investigators.
Clin Cardiol. 2019 Feb 1. doi: 10.1002/clc.23161. [Epub ahead of print]
PMID: 30706520 [PubMed – as supplied by publisher] Free Article



From Our Own…

Cardiovascular Risk Factors Associated With Venous Thromboembolism.

Gregson J, Kaptoge S, Bolton T, Pennells L, Willeit P, Burgess S, Bell S, Sweeting M, Rimm EB, Kabrhel C, Zöller B, Assmann G, Gudnason V, Folsom AR, Arndt V, Fletcher A, Norman PE, Nordestgaard BG, Kitamura A, Mahmoodi BK, Whincup PH, Knuiman M, Salomaa V, Meisinger C, Koenig W, Kavousi M, Völzke H, Cooper JA, Ninomiya T, Casiglia E, Rodriguez B, Ben-Shlomo Y, Després JP, Simons L, Barrett-Connor E, Björkelund C, Notdurfter M, Kromhout D, Price J, Sutherland SE, Sundström J, Kauhanen J, Gallacher J, Beulens JWJ, Dankner R, Cooper C, Giampaoli S, Deen JF, Gómez de la Cámara A, Kuller LH, Rosengren A, Svensson PJ, Nagel D, Crespo CJ, Brenner H, Albertorio-Diaz JR, Atkins R, Brunner EJ, Shipley M, Njølstad I, Lawlor DA, van der Schouw YT, Selmer RM, Trevisan M, Verschuren WMM, Greenland P, Wassertheil-Smoller S, Lowe GDO, Wood AM, Butterworth AS, Thompson SG, Danesh J, Di Angelantonio E, Meade T; Emerging Risk Factors Collaboration.
JAMA Cardiol. 2019 Jan 16. doi: 10.1001/jamacardio.2018.4537. [Epub ahead of print]


How the Results of a Randomized Trial of Catheter-Directed Thrombolysis Versus Anticoagulation alone for Submassive Pulmonary Embolism Would Affect Patient and Physician Decision Making: Report of an Online Survey.

Taslakian B, Li C, Goldhaber SZ, Mikkelsen KZ, Horowitz JM, Kabrhel C, Barnes GD, Sista AK.
J Clin Med. 2019 Feb 7;8(2). pii: E215. doi: 10.3390/jcm8020215.
PMID: 30736480 [PubMed] Free Article